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TAP1


Official Full Name
transporter 1, ATP binding cassette subfamily B member
Organism
Homo sapiens
Gene ID
6890
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Synonyms
APT1; PSF1; ABC17; ABCB2; PSF-1; RING4; TAP1N; MHC1D1; D6S114E; TAP1*0102N

Cat.No. Product Name Price
SHH423016 shRNA set against Mouse TAP1 (NM_013683.2) Inquiry
SHH423012 shRNA set against Human TAP1 (NM_000593.5) Inquiry
SHH423020 shRNA set against Rat TAP1 (NM_032055.4) Inquiry
SHL055957 shRNA set against Human TAP1(NM_000593.5) Inquiry
SHL055992 shRNA set against Mouse Tap1(NM_013683.1) Inquiry
SHW002821 shRNA set against Chicken TAP1 (NM_001135968) Inquiry
Cat.No. Product Name Price
CDCR337242 Human TAP1 ORF Clone(NM_000593.5) Inquiry
CDFG020068 Mouse Tap1 cDNA Clone(NM_001161730.1) Inquiry
CDFH019204 Human TAP1 cDNA Clone(NM_000593.5) Inquiry
CDFL013435 Mouse Tap1 cDNA Clone(NM_013683.2) Inquiry
CDFR012993 Rat Tap1 cDNA Clone(NM_032055.4) Inquiry
MiUTR1H-10175 TAP1 miRNA 3'UTR clone Inquiry
CDCB164296 Chicken TAP1 ORF Clone (NM_001135968) Inquiry
CDCB188369 Rabbit TAP1 ORF clone (XM_002714601.2) Inquiry
CDCH088764 Mouse Tap1 ORF clone (NM_001161730.1) Inquiry
CDCR252199 Mouse Tap1 ORF Clone(NM_013683.2) Inquiry
CDCR380007 Rat Tap1 ORF Clone(NM_032055.4) Inquiry
CDCS405777 Human TAP1 ORF Clone (BC014081) Inquiry
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