Pages
Products

RAD50


Official Full Name
RAD50 double strand break repair protein
Organism
Homo sapiens
Gene ID
10111
Background
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]
Synonyms
NBSLD; RAD502; hRad50

Cat.No. Product Name Price
SHH388984 shRNA set against Human RAD50 (NM_005732.3) Inquiry
SHR161922 shRNA set against Rat Rad50(NM_022246.1) Inquiry
SHR162022 shRNA set against Mouse Rad50(NM_009012.2) Inquiry
SHH388988 shRNA set against Mouse RAD50 (NM_009012.2) Inquiry
SHH388992 shRNA set against Rat RAD50 (NM_022246.1) Inquiry
Cat.No. Product Name Price
CDCH396280 Human RAD50 ORF clone(NM_005732.3) Inquiry
CDCR246422 Mouse Rad50 ORF Clone(NM_009012.2) Inquiry
CDFL011208 Mouse Rad50 cDNA Clone(NM_009012.2) Inquiry
CDFR011929 Rat Rad50 cDNA Clone(NM_022246.1) Inquiry
MiUTR1M-09885 RAD50 miRNA 3'UTR clone Inquiry
MiUTR3H-06460 RAD50 miRNA 3'UTR clone Inquiry
CDCB195133 Rabbit RAD50 ORF clone (NM_001171348.1) Inquiry
CDCR378932 Rat Rad50 ORF Clone(NM_022246.1) Inquiry
Quick Inquiry