Pages
Products

INSR


Official Full Name
insulin receptor
Organism
Homo sapiens
Gene ID
3643
Background
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Synonyms
HHF5; CD220

Cat.No. Product Name Price
SHH319905 shRNA set against Human INSR (NM_000208.2) Inquiry
SHH319909 shRNA set against Mouse INSR (NM_010568.2) Inquiry
SHH319913 shRNA set against Rat INSR (NM_017071.2) Inquiry
SHL179202 shRNA set against Human INSR(NM_001079817.1) Inquiry
SHL179220 shRNA set against Mouse Insr(NM_010568.2) Inquiry
SHL179310 shRNA set against Human INSR(NM_000208.2) Inquiry
Cat.No. Product Name Price
CDCS405503 Human INSR ORF Clone (BC117172) Inquiry
CDFH009295 Human INSR cDNA Clone(NM_001079817.1) Inquiry
CDFL006246 Mouse Insr cDNA Clone(NM_010568.2) Inquiry
CDFR011138 Rat Insr cDNA Clone(NM_017071.2) Inquiry
MiUTR1H-04966 INSR miRNA 3'UTR clone Inquiry
MiUTR1H-04967 INSR miRNA 3'UTR clone Inquiry
MiUTR1M-06064 INSR miRNA 3'UTR clone Inquiry
CDCB195569 Rabbit INSR ORF clone (XM_008249177.1) Inquiry
CDCL121157 Mouse INSR ORF clone (NM_001079817.1) Inquiry
CDCL121159 Human INSR ORF clone (NM_000208.2) Inquiry
CDCL184936 Mouse INSR ORF clone(NM_010568.2) Inquiry
CDCL184937 Rat INSR ORF clone(NM_017071.2) Inquiry
Cat.No. Product Name Price
CC-695 INSR Easy KO Kit Inquiry
Quick Inquiry