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BBC3


Official Full Name
BCL2 binding component 3
Organism
Homo sapiens
Gene ID
27113
Background
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Synonyms
JFY1; PUMA; JFY-1

Cat.No. Product Name Price
SHG092185 shRNA set against Rat Bbc3(NM_173837.2) Inquiry
SHW010299 shRNA set against Danio rerio BBC3 (NM_001045472) Inquiry
SHH245074 shRNA set against Human BBC3 (NM_014417.4) Inquiry
SHH245078 shRNA set against Mouse BBC3 (NM_133234.2) Inquiry
SHH245082 shRNA set against Rat BBC3 (NM_173837.2) Inquiry
Cat.No. Product Name Price
CDCB171774 Danio rerio BBC3 ORF Clone (NM_001045472) Inquiry
CDCR381915 Rat Bbc3 ORF Clone(NM_173837.2) Inquiry
CDFR014828 Rat Bbc3 cDNA Clone(NM_173837.2) Inquiry
MiUTR1R-00518 BBC3 miRNA 3'UTR clone Inquiry
MiUTR4H-TG00737 BBC3 miRNA 3'UTR clone Inquiry
CDCB182139 Rabbit BBC3 ORF clone (XM_008250808.1) Inquiry
CDCR265120 Mouse Bbc3 ORF Clone(NM_133234.2) Inquiry
CDCR348584 Human BBC3 ORF Clone(NM_001127241.2) Inquiry
CDCR348586 Human BBC3 ORF Clone(NM_001127242.2) Inquiry
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