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APEX1


Official Full Name
apurinic/apyrimidinic endodeoxyribonuclease 1
Organism
Homo sapiens
Gene ID
328
Background
The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.[provided by RefSeq, Dec 2019]
Synonyms
APE; APX; APE1; APEN; APEX; HAP1; REF1

Cat.No. Product Name Price
SHG064459 shRNA set against Rat Apex1(NM_024148.1) Inquiry
SHH238174 shRNA set against Human APEX1 (NM_080649.2) Inquiry
SHH238178 shRNA set against Mouse APEX1 (NM_009687.2) Inquiry
SHH238182 shRNA set against Rat APEX1 (NM_024148.1) Inquiry
SHW003043 shRNA set against Chicken APEX1 (NM_001184759) Inquiry
SHW018479 shRNA set against Danio rerio APEX1 (NM_213421) Inquiry
Cat.No. Product Name Price
CDFR012278 Rat Apex1 cDNA Clone(NM_024148.1) Inquiry
MiUTR1R-00298 APEX1 miRNA 3'UTR clone Inquiry
MiUTR3H-00186 APEX1 miRNA 3'UTR clone Inquiry
MiUTR3H-00187 APEX1 miRNA 3'UTR clone Inquiry
MiUTR3H-00188 APEX1 miRNA 3'UTR clone Inquiry
SKO0304 APEX1 Validated sgRNA vector Inquiry
CDCB156187 Cynomolgus APEX1 ORF clone Inquiry
CDCB164518 Chicken APEX1 ORF Clone (NM_001184759) Inquiry
CDCB179954 Danio rerio APEX1 ORF Clone (NM_213421) Inquiry
CDCB188491 Rabbit APEX1 ORF clone (XM_008269300.1) Inquiry
CDCR379355 Rat Apex1 ORF Clone(NM_024148.1) Inquiry
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