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ADRB2


Official Full Name
adrenoceptor beta 2
Organism
Homo sapiens
Gene ID
154
Background
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]
Synonyms
BAR; ARB2; B2AR; ADRBR; ADRB2R; BETA2AR

Cat.No. Product Name Price
SHG044197 shRNA set against Rat Adrb2(NM_012492.2) Inquiry
SHH232754 shRNA set against Human ADRB2 (NM_000024.5) Inquiry
SHG044029 shRNA set against Mouse Adrb2(NM_007420.2) Inquiry
SHH232758 shRNA set against Mouse ADRB2 (NM_007420.2) Inquiry
SHH232762 shRNA set against Rat ADRB2 (NM_012492.2) Inquiry
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OE-PNDC000021 Human ADRB2 Nanodisc Inquiry
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MiUTR1R-00161 ADRB2 miRNA 3'UTR clone Inquiry
MiUTR3H-00256 ADRB2 miRNA 3'UTR clone Inquiry
CDCB193138 Rabbit ADRB2 ORF clone (XM_002710297.2) Inquiry
CDCR025208 Mouse Adrb2 ORF clone (NM_007420.2) Inquiry
CDCR377401 Rat Adrb2 ORF Clone(NM_012492.2) Inquiry
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