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TNK2


Official Full Name
tyrosine kinase non receptor 2
Organism
Homo sapiens
Gene ID
10188
Background
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
Synonyms
ACK; ACK1; ACK-1; p21cdc42Hs

Cat.No. Product Name Price
AD16698Z Human TNK2 adenoviral particles Inquiry
Cat.No. Product Name Price
SHH432272 shRNA set against Human TNK2 (NM_005781.4) Inquiry
SHG029521 shRNA set against Human TNK2(NM_001010938.1) Inquiry
SHG029539 shRNA set against Human TNK2(NM_005781.4) Inquiry
SHG029557 shRNA set against Mouse Tnk2(NM_016788.3) Inquiry
SHH432276 shRNA set against Mouse TNK2 (NM_016788.3) Inquiry
SHH432280 shRNA set against Rat TNK2 (NM_001008336.1) Inquiry
SHL086046 shRNA set against Rat Tnk2(NM_001008336.1) Inquiry
SHW010853 shRNA set against Danio rerio TNK2B (NM_001080017) Inquiry
Cat.No. Product Name Price
CDFH020047 Human TNK2 cDNA Clone(NM_001010938.1) Inquiry
CDFH020048 Human TNK2 cDNA Clone(NM_005781.4) Inquiry
CDFH020049 Human TNK2 cDNA Clone(NM_005781.4) Inquiry
CDFL014117 Mouse Tnk2 cDNA Clone(NM_016788.3) Inquiry
CDFR001798 Rat Tnk2 cDNA Clone(NM_001008336.1) Inquiry
MiUTR1H-10612 TNK2 miRNA 3'UTR clone Inquiry
MiUTR1H-10613 TNK2 miRNA 3'UTR clone Inquiry
MiUTR1M-12015 TNK2 miRNA 3'UTR clone Inquiry
MiUTR1R-08131 TNK2 miRNA 3'UTR clone Inquiry
CDCB172328 Danio rerio TNK2B ORF Clone (NM_001080017) Inquiry
CDCB187686 Rabbit TNK2 ORF clone (XM_008266727.1) Inquiry
CDCR023758 Human TNK2 ORF clone (NM_001010938.1) Inquiry
CDCR236400 Mouse Tnk2 ORF Clone(NM_001110147.1) Inquiry
CDCR253099 Mouse Tnk2 ORF Clone(NM_016788.3) Inquiry
CDCR368865 Rat Tnk2 ORF Clone(NM_001008336.1) Inquiry
CDCS406449 Human TNK2 ORF Clone (BC028164) Inquiry
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