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SETD2


Official Full Name
SET domain containing 2, histone lysine methyltransferase
Organism
Homo sapiens
Gene ID
29072
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Synonyms
LLS; HYPB; SET2; HIF-1; HIP-1; KMT3A; MRD70; RAPAS; HBP231; HSPC069; p231HBP

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LV25127L human SETD2 (NM_014159) lentivirus particles Inquiry
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SHH405588 shRNA set against Human SETD2 (NM_014159.6) Inquiry
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CDCB186976 Rabbit SETD2 ORF clone (XM_008260951.1) Inquiry
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SKO0768 SETD2 Validated sgRNA vector Inquiry
CDCL186152 Human SETD2 ORF clone(NM_014159.6) Inquiry
CDCR374871 Rat Setd2 ORF Clone(NM_001108189.1) Inquiry
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