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CYP1A1


Official Full Name
cytochrome P450 family 1 subfamily A member 1
Organism
Homo sapiens
Gene ID
1543
Background
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
Synonyms
AHH; AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX

Cat.No. Product Name Price
SHG047357 shRNA set against Rat Cyp1a1(NM_012540.2) Inquiry
SHH272865 shRNA set against Human CYP1A1 (NM_000499.3) Inquiry
SHH272869 shRNA set against Mouse CYP1A1 (NM_009992.4) Inquiry
SHH272873 shRNA set against Rat CYP1A1 (NM_012540.2) Inquiry
SHW005646 shRNA set against Chicken CYP1A1 (NM_205146) Inquiry
SHW015269 shRNA set against Danio rerio CYP1A (NM_131879) Inquiry
Cat.No. Product Name Price
CDCR377287 Rat Cyp1a1 ORF Clone(NM_012540.2) Inquiry
CDCS405698 Human CYP1A1 ORF Clone (BC023019) Inquiry
CDFR010360 Rat Cyp1a1 cDNA Clone(NM_012540.2) Inquiry
MiUTR1H-02610 CYP1A1 miRNA 3'UTR clone Inquiry
MiUTR1R-01313 CYP1A1 miRNA 3'UTR clone Inquiry
CDCB160282 Human CYP1A1 ORF clone (NM_000499) Inquiry
CDCB167121 Chicken CYP1A1 ORF Clone (NM_205146) Inquiry
CDCB176744 Danio rerio CYP1A ORF Clone (NM_131879) Inquiry
CDCB181236 Rabbit LOC100328613 ORF clone (XM_008252400.1) Inquiry
CDCH384643 Mouse CYP1A1 ORF clone(NM_001136059.2) Inquiry
CDCR025838 Human CYP1A1 ORF clone (NM_000499.3) Inquiry
CDCR248235 Mouse Cyp1a1 ORF Clone(NM_009992.4) Inquiry
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