Pages
Products

WT1


Official Full Name
WT1 transcription factor
Organism
Homo sapiens
Gene ID
7490
Background
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]
Synonyms
GUD; AWT1; WAGR; WT-1; WT33; NPHS4; WIT-2

Cat.No. Product Name Price
SHH447524 shRNA set against Human WT1 (NM_000378.4) Inquiry
SHH447528 shRNA set against Mouse WT1 (NM_144783.2) Inquiry
SHH447532 shRNA set against Rat WT1 (NM_031534.2) Inquiry
SHL136938 shRNA set against Rat Wt1(NM_031534.2) Inquiry
SHL136992 shRNA set against Mouse Wt1(NM_144783.2) Inquiry
SHW005712 shRNA set against Chicken WT1 (NM_205216) Inquiry
SHW009523 shRNA set against Danio rerio WT1B (NM_001039634) Inquiry
SHW014560 shRNA set against Danio rerio WT1A (NM_131046) Inquiry
Cat.No. Product Name Price
CDCB160153 Human WT1 ORF clone (BC032861) Inquiry
MiUTR3H-08968 WT1 miRNA 3'UTR clone Inquiry
MiUTR1R-08601 WT1 miRNA 3'UTR clone Inquiry
MiUTR1M-12819 WT1 miRNA 3'UTR clone Inquiry
CDFR012693 Rat Wt1 cDNA Clone(NM_031534.2) Inquiry
CDFL015170 Mouse Wt1 cDNA Clone(NM_144783.2) Inquiry
CDCS405623 Human WT1 ORF Clone (BC032861) Inquiry
MiUTR3H-08969 WT1 miRNA 3'UTR clone Inquiry
MiUTR3H-08970 WT1 miRNA 3'UTR clone Inquiry
CDCR358872 Human WT1 ORF Clone(NM_001198551.1) Inquiry
CDCH101572 human WT1 ORF clone (NM_001198552.1) Inquiry
CDCH101564 Mouse Wt1 ORF clone (NM_144783.2) Inquiry
CDCB189751 Rabbit WT1 ORF clone (XM_008269425.1) Inquiry
CDCB176035 Danio rerio WT1A ORF Clone (NM_131046) Inquiry
CDCB170998 Danio rerio WT1B ORF Clone (NM_001039634) Inquiry
CDCB167187 Chicken WT1 ORF Clone (NM_205216) Inquiry
CDCR379726 Rat Wt1 ORF Clone(NM_031534.2) Inquiry
Quick Inquiry