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wt1b


Official Full Name
WT1 transcription factor b
Organism
Danio rerio
Gene ID
568416
Background
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including fin regeneration; kidney development; and macrophage chemotaxis. Predicted to be located in cytoplasm and nuclear speck. Is expressed in several structures, including eye; heart; intermediate mesoderm; pleuroperitoneal region; and podocyte. Human ortholog(s) of this gene implicated in several diseases, including Denys-Drash syndrome; Frasier syndrome; malignant mesothelioma; nephroblastoma (multiple); and nephrotic syndrome type 4. Orthologous to human WT1 (WT1 transcription factor). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
wt1; zgc:152697; si:ch211-160j6.3

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