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TFAP2A

Official Full Name
transcription factor AP-2 alpha
Organism
Homo sapiens
GeneID
7020
Background
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
Synonyms
AP-2; BOFS; AP2TF; TFAP2; AP-2alpha;

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