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TDG


Official Full Name
thymine DNA glycosylase
Organism
Homo sapiens
Gene ID
6996
Background
The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008]
Synonyms
hTDG

Cat.No. Product Name Price
SHL063594 shRNA set against Mouse Tdg(NM_172552.3) Inquiry
SHW005258 shRNA set against Chicken TDG (NM_204750) Inquiry
SHH425248 shRNA set against Mouse TDG (NM_011561.2) Inquiry
SHH425252 shRNA set against Rat TDG (NM_053729.1) Inquiry
SHL063516 shRNA set against Rat Tdg(NM_053729.1) Inquiry
SHL063552 shRNA set against Mouse Tdg(NM_011561.2) Inquiry
SHW008777 shRNA set against Danio rerio TDG.1 (NM_001020751) Inquiry
Cat.No. Product Name Price
CDCH089988 Mouse Tdg ORF clone (NM_011561.2) Inquiry
CDCR380382 Rat Tdg ORF Clone(NM_053729.1) Inquiry
CDFR013414 Rat Tdg cDNA Clone(NM_053729.1) Inquiry
MiUTR1H-10297 TDG miRNA 3'UTR clone Inquiry
MiUTR1M-11648 TDG miRNA 3'UTR clone Inquiry
MiUTR1M-11649 TDG miRNA 3'UTR clone Inquiry
MiUTR1R-07953 TDG miRNA 3'UTR clone Inquiry
SKO0830 TDG Validated sgRNA vector Inquiry
CDCB166733 Chicken TDG ORF Clone (NM_204750) Inquiry
CDCB170252 Danio rerio TDG.1 ORF Clone (NM_001020751) Inquiry
CDCB184363 Rabbit TDG ORF clone (XM_008256998.1) Inquiry
CDCR271192 Mouse Tdg ORF Clone(NM_172552.3) Inquiry
CDCS411196 Human TDG ORF Clone (BC037557) Inquiry
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