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TGFΒR2


Official Full Name
transforming growth factor beta receptor 2
Organism
Homo sapiens
Gene ID
7048
Background
The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
Synonyms
TGFBR2; AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TBRII; TBR-ii; TGFR-2; tbetaR-II; TGFbeta-RII

Cat.No. Product Name Price
SHH426448 shRNA set against Mouse TGFBR2 (NM_009371.3) Inquiry
SHH413708 shRNA set against Human SMTNL2 (NM_198501.2) Inquiry
SHH413712 shRNA set against Mouse SMTNL2 (NM_177776.3) Inquiry
SHH426444 shRNA set against Human TGFBR2 (NM_003242.5) Inquiry
SHH426452 shRNA set against Rat TGFBR2 (NM_031132.3) Inquiry
SHL067800 shRNA set against Rat Tgfbr2(NM_031132.3) Inquiry
SHL067868 shRNA set against Human TGFBR2(NM_001024847.2) Inquiry
SHL067904 shRNA set against Human TGFBR2(NM_003242.5) Inquiry
SHW005922 shRNA set against Chicken TGFBR2 (NM_205428) Inquiry
SHW015530 shRNA set against Danio rerio TGFBR2 (NM_182855) Inquiry
Cat.No. Product Name Price
SKO0187 TGFBR2 Validated sgRNA vector Inquiry
MiUTR1R-07989 TGFBR2 miRNA 3'UTR clone Inquiry
MiUTR1M-03599 SMTNL2 miRNA 3'UTR clone Inquiry
MiUTR1H-10353 TGFBR2 miRNA 3'UTR clone Inquiry
MiUTR1H-09667 SMTNL2 miRNA 3'UTR clone Inquiry
CDFR012602 Rat Tgfbr2 cDNA Clone(NM_031132.3) Inquiry
CDFL013702 Mouse Tgfbr2 cDNA Clone(NM_029575.3) Inquiry
CDFL013701 Mouse Tgfbr2 cDNA Clone(NM_009371.3) Inquiry
CDFH018205 Human SMTNL2 cDNA Clone(NM_001114974.1) Inquiry
MiUTR3H-02278 TGFBR2 miRNA 3'UTR clone Inquiry
CDCS406674 Human TGFBR2 ORF Clone (BC040499) Inquiry
CDCR348166 Human SMTNL2 ORF Clone(NM_001114974.1) Inquiry
CDCR262604 Mouse Tgfbr2 ORF Clone(NM_029575.3) Inquiry
CDCL186426 Human TGFβR2 ORF clone(NM_003242.5) Inquiry
CDCL186423 Rat TGFBR2 ORF clone(NM_031132.3) Inquiry
CDCL186417 Human TGF-beta 2 ORF clone(NM_003238.3) Inquiry
CDCH090576 human TGFBR2 ORF clone (NM_001024847.2) Inquiry
CDCH083790 Mouse Smtnl2 ORF clone (NM_177776.3) Inquiry
CDCH083786 human SMTNL2 ORF clone (NM_198501.2) Inquiry
CDCB188577 Rabbit SMTNL2 ORF clone (XM_002718852.2) Inquiry
CDCB180635 Rabbit TGFBR2 ORF clone (NM_001177748.1) Inquiry
CDCB177005 Danio rerio TGFBR2 ORF Clone (NM_182855) Inquiry
CDCB167397 Chicken TGFBR2 ORF Clone (NM_205428) Inquiry
CDCR247105 Mouse Tgfbr2 ORF Clone(NM_009371.3) Inquiry
CDCB156584 Cynomolgus TGFBR2 ORF clone Inquiry
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