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TGF-BETA 3


Official Full Name
LDL receptor related protein 1
Organism
Homo sapiens
Gene ID
4035
Background
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]
Synonyms
LRP1; APR; KPA; LRP; A2MR; CD91; DDH3; APOER; LRP1A; TGFBR5; IGFBP3R; IGFBP-3R; IGFBP3R1

Cat.No. Product Name Price
SHH426416 shRNA set against Rat TGFB3 (NM_013174.2) Inquiry
SHH426408 shRNA set against Human TGFB3 (NM_003239.2) Inquiry
SHH426412 shRNA set against Mouse TGFB3 (NM_009368.3) Inquiry
SHW005947 shRNA set against Chicken TGFB3 (NM_205454) Inquiry
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Cat.No. Product Name Price
CDCB177097 Danio rerio TGFB3 ORF Clone (NM_194386) Inquiry
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MiUTR3H-02283 TGFB3 miRNA 3'UTR clone Inquiry
CDCB156502 Canine TGFB3 ORF clone (XM_849026.2) Inquiry
CDCB156901 Cynomolgus TGFB3 ORF clone Inquiry
CDCB167422 Chicken TGFB3 ORF Clone (NM_205454) Inquiry
CDCB180615 Rabbit TGFB3 ORF clone (XM_002719635.2) Inquiry
CDCG000252 Mouse TGFB3 ORF clone(NM_009368.3) Inquiry
CDCL186415 Rat TGFB3 ORF clone(NM_013174.2) Inquiry
CDCL186418 Human TGF-beta 3 ORF clone(NM_003239.2) Inquiry
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