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TGFB3


Official Full Name
transforming growth factor beta 3
Organism
Homo sapiens
Gene ID
7043
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]
Synonyms
ARVD; LDS5; RNHF; ARVD1; TGF-beta3

Cat.No. Product Name Price
SHH426416 shRNA set against Rat TGFB3 (NM_013174.2) Inquiry
SHH426408 shRNA set against Human TGFB3 (NM_003239.2) Inquiry
SHH426412 shRNA set against Mouse TGFB3 (NM_009368.3) Inquiry
SHW005947 shRNA set against Chicken TGFB3 (NM_205454) Inquiry
SHW015622 shRNA set against Danio rerio TGFB3 (NM_194386) Inquiry
Cat.No. Product Name Price
CDCB177097 Danio rerio TGFB3 ORF Clone (NM_194386) Inquiry
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MiUTR3H-02283 TGFB3 miRNA 3'UTR clone Inquiry
CDCB156502 Canine TGFB3 ORF clone (XM_849026.2) Inquiry
CDCB156901 Cynomolgus TGFB3 ORF clone Inquiry
CDCB167422 Chicken TGFB3 ORF Clone (NM_205454) Inquiry
CDCB180615 Rabbit TGFB3 ORF clone (XM_002719635.2) Inquiry
CDCG000252 Mouse TGFB3 ORF clone(NM_009368.3) Inquiry
CDCL186415 Rat TGFB3 ORF clone(NM_013174.2) Inquiry
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