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TAGLN


Official Full Name
transgelin
Organism
Homo sapiens
Gene ID
6876
Background
This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]
Synonyms
SM22; SMCC; TGLN; TAGLN1; WS3-10; SM22-alpha

Cat.No. Product Name Price
SHH422864 shRNA set against Human TAGLN (NM_003186.3) Inquiry
SHH422868 shRNA set against Mouse TAGLN (NM_011526.5) Inquiry
SHH422872 shRNA set against Rat TAGLN (NM_031549.2) Inquiry
SHL055430 shRNA set against Rat Tagln(NM_031549.2) Inquiry
SHL055431 shRNA set against Rat Tagln(NM_031549.2) Inquiry
SHL055448 shRNA set against Mouse Tagln(NM_011526.4) Inquiry
SHL055484 shRNA set against Human TAGLN(NM_001001522.1) Inquiry
SHL055485 shRNA set against Human TAGLN(NM_001001522.1) Inquiry
SHW005986 shRNA set against Chicken TAGLN (NM_205494) Inquiry
SHW010295 shRNA set against Danio rerio TAGLN (NM_001045467) Inquiry
Cat.No. Product Name Price
MiUTR3H-03649 TAGLN miRNA 3'UTR clone Inquiry
MiUTR1H-10167 TAGLN miRNA 3'UTR clone Inquiry
CDFR012707 Rat Tagln cDNA Clone(NM_031549.2) Inquiry
CDFH019189 Human TAGLN cDNA Clone(NM_003186.3) Inquiry
CDFH019188 Human TAGLN cDNA Clone(NM_001001522.1) Inquiry
CDCH016515 Mouse TAGLN ORF clone(NM_011526.5) Inquiry
MiUTR1R-07888 TAGLN miRNA 3'UTR clone Inquiry
CDCS406089 Human TAGLN ORF Clone (BC010946) Inquiry
CDCS406088 Human TAGLN ORF Clone (BC004927) Inquiry
CDCR379740 Rat Tagln ORF Clone(NM_031549.2) Inquiry
CDCH088662 human TAGLN ORF clone (NM_001001522.1) Inquiry
CDCB195676 Rabbit LOC100009332 ORF clone (XM_002717199.2) Inquiry
CDCB182281 Rabbit TAGLN ORF clone (XM_002708381.2) Inquiry
CDCB171770 Danio rerio TAGLN ORF Clone (NM_001045467) Inquiry
CDCB167461 Chicken TAGLN ORF Clone (NM_205494) Inquiry
CDCR285083 Human TAGLN ORF Clone(NM_003186.3) Inquiry
CDCB158538 Human TAGLN ORF clone (BC004927) Inquiry
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