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SIRT1


Official Full Name
sirtuin 1
Organism
Homo sapiens
Gene ID
23411
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Synonyms
SIR2; SIR2L1; SIR2alpha

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SHH407728 shRNA set against Human SIRT1 (NM_012238.4) Inquiry
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SHR226218 shRNA set against Mouse Sirt1(NM_001159589.1) Inquiry
SHR226482 shRNA set against Human SIRT1(NM_001142498.1) Inquiry
SHW000180 shRNA set against Chicken SIRT1 (NM_001004767) Inquiry
Cat.No. Product Name Price
CDCH080402 human SIRT1 ORF clone (NM_001142498.1) Inquiry
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CDFH017598 Human SIRT1 cDNA Clone(NM_001142498.1) Inquiry
CDFL012321 Mouse Sirt1 cDNA Clone(NM_019812.2) Inquiry
MiUTR1H-09412 SIRT1 miRNA 3'UTR clone Inquiry
MiUTR1M-10714 SIRT1 miRNA 3'UTR clone Inquiry
MiUTR3H-06840 SIRT1 miRNA 3'UTR clone Inquiry
SKO0772 SIRT1 Validated sgRNA vector Inquiry
CDCB161655 Chicken SIRT1 ORF Clone (NM_001004767) Inquiry
CDCB188298 Rabbit SIRT1 ORF clone (XM_008270059.1) Inquiry
CDCH080346 Mouse Sirt1 ORF clone (NM_001159589.1) Inquiry
CDCR254429 Mouse Sirt1 ORF Clone(NM_019812.2) Inquiry
CDCS408281 Human SIRT1 ORF Clone (BC012499) Inquiry
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