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SESN1


Official Full Name
sestrin 1
Organism
Homo sapiens
Gene ID
27244
Background
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Synonyms
PA26; SEST1

Cat.No. Product Name Price
SHH405508 shRNA set against Mouse SESN1 (NM_001013370.2) Inquiry
SHW006656 shRNA set against Danio rerio SESN1 (NM_001002660) Inquiry
SHH405504 shRNA set against Human SESN1 (NM_014454.2) Inquiry
SHH405512 shRNA set against Rat SESN1 (NM_001106396.1) Inquiry
Cat.No. Product Name Price
CDCB156285 Cynomolgus SESN1 ORF clone (XM_001092927.2) Inquiry
CDCH078966 Mouse Sesn1 ORF clone (NM_001162908.1) Inquiry
CDFR006135 Rat Sesn1 cDNA Clone(NM_001106396.1) Inquiry
MiUTR3H-08219 SESN1 miRNA 3'UTR clone Inquiry
CDCB168131 Danio rerio SESN1 ORF Clone (NM_001002660) Inquiry
CDCB191139 Rabbit SESN1 ORF clone (XM_008263340.1) Inquiry
CDCH078960 human SESN1 ORF clone (NM_001199934.1) Inquiry
CDCH078962 human SESN1 ORF clone (NM_001199933.1) Inquiry
CDCR373197 Rat Sesn1 ORF Clone(NM_001106396.1) Inquiry
CDCS409518 Human SESN1 ORF Clone (BC113569) Inquiry
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