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RUNX2


Official Full Name
RUNX family transcription factor 2
Organism
Homo sapiens
Gene ID
860
Background
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
Synonyms
CCD; AML3; CCD1; CLCD; OSF2; CBFA1; OSF-2; PEA2aA; PEBP2aA; CBF-alpha-1

Cat.No. Product Name Price
SHH400788 shRNA set against Mouse RUNX2 (NM_009820.5) Inquiry
SHH400784 shRNA set against Human RUNX2 (NM_004348.3) Inquiry
SHH400792 shRNA set against Rat RUNX2 (NM_053470.2) Inquiry
SHW004647 shRNA set against Chicken RUNX2 (NM_204128) Inquiry
Cat.No. Product Name Price
CDCH399382 Mouse RUNX2 ORF clone(NM_009820.5) Inquiry
CDCH399383 Rat RUNX2 ORF clone(NM_053470.2) Inquiry
CDFH016798 Human RUNX2 cDNA Clone(NM_004348.3) Inquiry
MiUTR1H-09081 RUNX2 miRNA 3'UTR clone Inquiry
MiUTR1R-07142 RUNX2 miRNA 3'UTR clone Inquiry
MiUTR3H-03189 RUNX2 miRNA 3'UTR clone Inquiry
CDCB166122 Chicken RUNX2 ORF Clone (NM_204128) Inquiry
CDCB195559 Rabbit RUNX2 ORF clone (XM_008262992.1) Inquiry
CDCH076396 human RUNX2 ORF clone (NM_001024630.3) Inquiry
CDCH076398 human RUNX2 ORF clone (NM_001015051.3) Inquiry
CDCH399380 Mouse RUNX2 ORF clone(NM_001145920.2) Inquiry
CDCR238262 Mouse Runx2 ORF Clone(NM_001146038.2) Inquiry
CDCR287839 Human RUNX2 ORF Clone(NM_004348.3) Inquiry
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