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PLCG1


Official Full Name
phospholipase C gamma 1
Organism
Homo sapiens
Gene ID
5335
Background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
IDAA; PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1

Cat.No. Product Name Price
SHH377222 shRNA set against Mouse Plcg1 (NM_021280.3) Inquiry
SHH377216 shRNA set against Human Plcg1 (NM_002660.2) Inquiry
SHH377224 shRNA set against Rat Plcg1 (NM_013187.1) Inquiry
SHR120138 shRNA set against Human PLCG1(NM_002660.2) Inquiry
SHR120156 shRNA set against Mouse Plcg1(NM_021280.3) Inquiry
SHR120448 shRNA set against Rat Plcg1(NM_013187.1) Inquiry
SHR120540 shRNA set against Human PLCG1(NM_182811.1) Inquiry
SHW015643 shRNA set against Danio rerio PLCG1 (NM_194407) Inquiry
Cat.No. Product Name Price
CDCB177118 Danio rerio PLCG1 ORF Clone (NM_194407) Inquiry
CDCH064672 human PLCG1 ORF clone (NM_002660.2) Inquiry
CDFG010855 Human PLCG1 cDNA Clone(NM_182811.1) Inquiry
CDFH014463 Human PLCG1 cDNA Clone(NM_002660.2) Inquiry
CDFR010972 Rat Plcg1 cDNA Clone(NM_013187.1) Inquiry
MiUTR1H-07981 PLCG1 miRNA 3'UTR clone Inquiry
MiUTR1H-07982 PLCG1 miRNA 3'UTR clone Inquiry
MiUTR1M-09305 PLCG1 miRNA 3'UTR clone Inquiry
MiUTR1R-05897 PLCG1 miRNA 3'UTR clone Inquiry
CDCB187908 Rabbit PLCG1 ORF clone (XM_008274489.1) Inquiry
CDCH064674 human PLCG1 ORF clone (NM_182811.1) Inquiry
CDCH064676 Mouse Plcg1 ORF clone (NM_021280.3) Inquiry
CDCR378070 Rat Plcg1 ORF Clone(NM_013187.1) Inquiry
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