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PTPRM


Official Full Name
protein tyrosine phosphatase receptor type M
Organism
Homo sapiens
Gene ID
5797
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Synonyms
RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU

Cat.No. Product Name Price
SHH386768 shRNA set against Human PTPRM (NM_002845.3) Inquiry
SHH386772 shRNA set against Mouse PTPRM (NM_008984.2) Inquiry
SHH386776 shRNA set against Rat PTPRM (NM_001168632.1) Inquiry
Cat.No. Product Name Price
CDCH069916 human PTPRM ORF clone (NM_001105244.1) Inquiry
CDCH395922 Rat PTPRM ORF clone(NM_001168632.1) Inquiry
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MiUTR1H-08478 PTPRM miRNA 3'UTR clone Inquiry
MiUTR3H-01896 PTPRM miRNA 3'UTR clone Inquiry
CDCB183745 Rabbit PTPRM ORF clone (XM_008261057.1) Inquiry
CDCH069918 human PTPRM ORF clone (NM_002845.3) Inquiry
CDCR246499 Mouse Ptprm ORF Clone(NM_008984.2) Inquiry
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