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PTPRC


Official Full Name
protein tyrosine phosphatase receptor type C
Organism
Homo sapiens
Gene ID
5788
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Synonyms
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105

Cat.No. Product Name Price
SHH386664 shRNA set against Mouse PTPRC (NM_011210.4) Inquiry
SHH386668 shRNA set against Rat PTPRC (NM_001109887.1) Inquiry
SHW004930 shRNA set against Chicken PTPRC (NM_204417) Inquiry
Cat.No. Product Name Price
MiUTR3H-01309 PTPRC miRNA 3'UTR clone Inquiry
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CDFR009210 Rat Ptprc cDNA Clone(NM_001109890.1) Inquiry
CDFR009209 Rat Ptprc cDNA Clone(NM_001109889.1) Inquiry
CDFR009208 Rat Ptprc cDNA Clone(NM_001109888.1) Inquiry
CDFR009207 Rat Ptprc cDNA Clone(NM_001109887.1) Inquiry
CDCR250289 Mouse Ptprc ORF Clone(NM_011210.4) Inquiry
MiUTR3H-01308 PTPRC miRNA 3'UTR clone Inquiry
CDCR381260 Rat Ptprc ORF Clone(NM_138507.2) Inquiry
CDCR376255 Rat Ptprc ORF Clone(NM_001109888.1) Inquiry
CDCR376254 Rat Ptprc ORF Clone(NM_001109887.1) Inquiry
CDCR236776 Mouse Ptprc ORF Clone(NM_001111316.2) Inquiry
CDCL185913 Rat PTPRC ORF clone(NM_001109890.1) Inquiry
CDCH069844 human PTPRC ORF clone (NM_002838.4) Inquiry
CDCB182600 Rabbit PTPRC ORF clone (XM_008268698.1) Inquiry
CDCB166405 Chicken PTPRC ORF Clone (NM_204417) Inquiry
CDCR376256 Rat Ptprc ORF Clone(NM_001109889.1) Inquiry
CDCB157155 Mouse PTPRC ORF clone (NM_011210.3) Inquiry
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