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PAM


Official Full Name
peptidylglycine alpha-amidating monooxygenase
Organism
Homo sapiens
Gene ID
5066
Background
This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Synonyms
PAL; PHM; PAM-1

Cat.No. Product Name Price
SHH370288 shRNA set against Human PAM (NM_000919.3) Inquiry
SHR086530 shRNA set against Human PAM(NM_000919.3) Inquiry
SHH370292 shRNA set against Mouse PAM (NM_013626.3) Inquiry
SHH370296 shRNA set against Rat PAM (NM_013000.2) Inquiry
SHR086574 shRNA set against Rat Pam(NM_013000.2) Inquiry
SHR086656 shRNA set against Mouse Pam(NM_013626.3) Inquiry
Cat.No. Product Name Price
CDCB159623 Human PAM ORF clone (BC018127) Inquiry
CDCB186673 Rabbit PAM ORF clone (XM_008261971.1) Inquiry
CDCR316870 Human PAM ORF Clone(NM_138766.2) Inquiry
CDCR377884 Rat Pam ORF Clone(NM_013000.2) Inquiry
CDFH013660 Human PAM cDNA Clone(NM_001177306.1) Inquiry
CDFL009868 Mouse Pam cDNA Clone(NM_013626.3) Inquiry
CDFR010807 Rat Pam cDNA Clone(NM_013000.2) Inquiry
MiUTR1H-07485 PAM miRNA 3'UTR clone Inquiry
MiUTR1M-08877 PAM miRNA 3'UTR clone Inquiry
MiUTR1R-05610 PAM miRNA 3'UTR clone Inquiry
SKO0026 PAM Validated sgRNA vector Inquiry
CDCL145735 Mouse PAM ORF clone (NM_001177306.1) Inquiry
CDCR252008 Mouse Pam ORF Clone(NM_013626.3) Inquiry
CDCR316996 Human PAM ORF Clone(NM_138822.2) Inquiry
CDCS405992 Human PAM ORF Clone (BC018127) Inquiry
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