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NEIL3

Official Full Name
nei like DNA glycosylase 3
Organism
Homo sapiens
GeneID
55247
Background
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]
Synonyms
FGP2; FPG2; NEI3; ZGRF3; hFPG2; hNEI3;

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