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MTHFD1


Official Full Name
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
Organism
Homo sapiens
Gene ID
4522
Background
This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq, Jul 2008]
Synonyms
CIMAH; MTHFC; MTHFD

Cat.No. Product Name Price
SHH206093 shRNA set against Rat Mthfd1(NM_022508.1) Inquiry
SHH346312 shRNA set against Human MTHFD1 (NM_005956.3) Inquiry
SHH346316 shRNA set against Mouse MTHFD1 (NM_138745.2) Inquiry
SHH346320 shRNA set against Rat MTHFD1 (NM_022508.1) Inquiry
SHW002305 shRNA set against Chicken MTHFD1 (NM_001039303) Inquiry
Cat.No. Product Name Price
CDFR011865 Rat Mthfd1 cDNA Clone(NM_022508.1) Inquiry
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CDCB189450 Rabbit MTHFD1 ORF clone (XM_008271884.1) Inquiry
CDCH390792 Mouse MTHFD1 ORF clone(NM_138745.2) Inquiry
CDCL134959 Mouse MTHFD1 ORF clone (NM_005956.3) Inquiry
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