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MBTPS1


Official Full Name
membrane bound transcription factor peptidase, site 1
Organism
Homo sapiens
Gene ID
8720
Background
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014]
Synonyms
S1P; PCSK8; SEDKF; SKI-1

Cat.No. Product Name Price
SHH180155 shRNA set against Rat Mbtps1(NM_053569.1) Inquiry
SHH180101 shRNA set against Human MBTPS1(NM_003791.2) Inquiry
SHH339003 shRNA set against Human MBTPS1 (NM_003791.2) Inquiry
SHH339007 shRNA set against Mouse MBTPS1 (NM_019709.4) Inquiry
SHH339011 shRNA set against Rat MBTPS1 (NM_053569.1) Inquiry
SHW015783 shRNA set against Danio rerio MBTPS1 (NM_199213) Inquiry
Cat.No. Product Name Price
CDCR286484 Human MBTPS1 ORF Clone(NM_003791.2) Inquiry
CDCR380329 Rat Mbtps1 ORF Clone(NM_053569.1) Inquiry
CDCS411461 Human MBTPS1 ORF Clone (BC026330) Inquiry
CDFH011173 Human MBTPS1 cDNA Clone(NM_003791.2) Inquiry
CDFR013292 Rat Mbtps1 cDNA Clone(NM_053569.1) Inquiry
MiUTR1H-06149 MBTPS1 miRNA 3'UTR clone Inquiry
MiUTR1R-03719 MBTPS1 miRNA 3'UTR clone Inquiry
CDCB177258 Danio rerio MBTPS1 ORF Clone (NM_199213) Inquiry
CDCB191306 Rabbit MBTPS1 ORF clone (XM_008252502.1) Inquiry
CDCR241536 Mouse Mbtps1 ORF Clone(NM_001167910.1) Inquiry
CDCR254223 Mouse Mbtps1 ORF Clone(NM_019709.4) Inquiry
CDCS411462 Human MBTPS1 ORF Clone (BC114961) Inquiry
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