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LITAF


Official Full Name
lipopolysaccharide induced TNF factor
Organism
Homo sapiens
Gene ID
9516
Background
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014]
Synonyms
PIG7; SIMPLE; TP53I7

Cat.No. Product Name Price
SHH330783 shRNA set against Human LITAF (NM_004862.3) Inquiry
SHH330787 shRNA set against Mouse LITAF (NM_019980.2) Inquiry
SHH330791 shRNA set against Rat LITAF (NM_001105735.2) Inquiry
SHW004783 shRNA set against Chicken LITAF (NM_204267) Inquiry
SHW006288 shRNA set against Danio rerio LITAF (NM_001002184) Inquiry
Cat.No. Product Name Price
CDCB166258 Chicken LITAF ORF Clone (NM_204267) Inquiry
CDCR008810 Mouse LITAF ORF clone(NM_019980.2) Inquiry
CDFH010441 Human LITAF cDNA Clone(NM_001136472.1) Inquiry
CDFH010442 Human LITAF cDNA Clone(NM_001136473.1) Inquiry
CDFR005471 Rat Litaf cDNA Clone(NM_001105735.2) Inquiry
MiUTR3H-06278 LITAF miRNA 3'UTR clone Inquiry
MiUTR3H-06279 LITAF miRNA 3'UTR clone Inquiry
SKO1021 LITAF Validated sgRNA vector Inquiry
CDCB159582 Human LITAF ORF clone (BC101401) Inquiry
CDCB167763 Danio rerio LITAF ORF Clone (NM_001002184) Inquiry
CDCB188508 Rabbit LITAF ORF clone (XM_008257723.1) Inquiry
CDCL127563 Human LITAF ORF clone (NM_001136473.1) Inquiry
CDCR350895 Human LITAF ORF Clone(NM_001136472.1) Inquiry
CDCR372517 Rat Litaf ORF Clone(NM_001105735.2) Inquiry
CDCS408195 Human LITAF ORF Clone (BC101401) Inquiry
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