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IL6ST


Official Full Name
interleukin 6 cytokine family signal transducer
Organism
Homo sapiens
Gene ID
3572
Background
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
Synonyms
CD130; GP130; HIES4; IMD94; STWS2; CDW130; HIES4A; HIES4B; IL-6RB; sGP130

Cat.No. Product Name Price
SHH319073 shRNA set against Human Il6st (NM_002184.3) Inquiry
SHH319077 shRNA set against Mouse Il6st (NM_010560.3) Inquiry
SHH319081 shRNA set against Rat Il6st (NM_001008725.3) Inquiry
SHW005377 shRNA set against Chicken IL6ST (NM_204871) Inquiry
SHW012189 shRNA set against Danio rerio IL6ST (NM_001113504) Inquiry
Cat.No. Product Name Price
CDCB157212 Mouse IL6ST ORF clone (NM_010560.2) Inquiry
CDCL184906 Rat IL6ST ORF clone(NM_001008725.3) Inquiry
CDFR001884 Rat Il6st cDNA Clone(NM_001008725.3) Inquiry
MiUTR1R-02654 IL6ST miRNA 3'UTR clone Inquiry
MiUTR3H-03563 IL6ST miRNA 3'UTR clone Inquiry
MiUTR3H-03564 IL6ST miRNA 3'UTR clone Inquiry
CDCB156556 Cynomolgus IL6ST ORF clone Inquiry
CDCB160629 Human IL6ST ORF clone (NM_002184.3) Inquiry
CDCB166852 Chicken IL6ST ORF Clone (NM_204871) Inquiry
CDCB173664 Danio rerio IL6ST ORF Clone (NM_001113504) Inquiry
CDCB188262 Rabbit IL6ST ORF clone (XM_008262226.1) Inquiry
CDCL120695 Human IL6ST ORF clone (NM_001190981.1) Inquiry
CDCR249214 Mouse Il6st ORF Clone(NM_010560.3) Inquiry
CDCS409229 Human IL6ST ORF Clone (BC117402) Inquiry
Cat.No. Product Name Price
CC-691 IL6ST Easy KO Kit Inquiry
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