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Grm5

Official Full Name
glutamate receptor, metabotropic 5
Organism
Mus musculus
GeneID
108071
Background
Enables protein tyrosine kinase activator activity. Involved in several processes, including cellular response to amyloid-beta; learning or memory; and positive regulation of calcium-mediated signaling. Acts upstream of or within learning; locomotory behavior; and regulation of long-term neuronal synaptic plasticity. Located in cytoplasm; neuron projection; and plasma membrane. Is active in Schaffer collateral - CA1 synapse and dendrite. Is expressed in central nervous system and retina. Used to study schizophrenia. Orthologous to human GRM5 (glutamate metabotropic receptor 5). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Grm5; Glu5R; Gprc1e; mGluR5; mGluR5b; 6430542K11Rik;

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