Pages
Products

FANCD2


Official Full Name
FA complementation group D2
Organism
Homo sapiens
Gene ID
2177
Background
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Synonyms
FA4; FAD; FACD; FAD2; FA-D2; FANCD

Cat.No. Product Name Price
SHH048935 shRNA set against Human FANCD2(NM_033084.3) Inquiry
SHH048953 shRNA set against Human FANCD2(NM_001018115.1) Inquiry
SHH292289 shRNA set against Human FANCD2 (NM_033084.3) Inquiry
SHH292293 shRNA set against Mouse FANCD2 (NM_001033244.3) Inquiry
SHH292297 shRNA set against Rat FANCD2 (NM_001001719.1) Inquiry
SHH048917 shRNA set against Rat Fancd2(NM_001001719.1) Inquiry
SHW002268 shRNA set against Chicken FANCD2 (NM_001039261) Inquiry
SHW017372 shRNA set against Danio rerio FANCD2 (NM_201341) Inquiry
Cat.No. Product Name Price
CC-543 Fancd2 Easy KO Kit Inquiry
Quick Inquiry