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ETV1


Official Full Name
ETS variant transcription factor 1
Organism
Homo sapiens
Gene ID
2115
Background
This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2016]
Synonyms
ER81

Cat.No. Product Name Price
SHH287673 shRNA set against Human ETV1 (NM_004956.4) Inquiry
SHH287677 shRNA set against Mouse ETV1 (NM_007960.4) Inquiry
SHH287681 shRNA set against Rat ETV1 (NM_001108709.2) Inquiry
SHW005422 shRNA set against Chicken ETV1 (NM_204917) Inquiry
SHW009175 shRNA set against Danio rerio ETV1 (NM_001030182) Inquiry
Cat.No. Product Name Price
MiUTR4H-TG03184 ETV1 miRNA 3'UTR clone Inquiry
CDFH006154 Human ETV1 cDNA Clone(NM_001163152.1) Inquiry
CDFH006153 Human ETV1 cDNA Clone(NM_001163151.1) Inquiry
CDFH006152 Human ETV1 cDNA Clone(NM_001163150.1) Inquiry
CDFH006151 Human ETV1 cDNA Clone(NM_001163149.1) Inquiry
CDFH006150 Human ETV1 cDNA Clone(NM_001163148.1) Inquiry
CDFH006149 Human ETV1 cDNA Clone(NM_001163147.1) Inquiry
CDFG022246 Mouse Etv1 cDNA Clone(BC005645) Inquiry
CDFG020220 Mouse Etv1 cDNA Clone(NM_001163154.1) Inquiry
CDFR008297 Rat Etv1 cDNA Clone(NM_001108709.2) Inquiry
CDCS408714 Human ETV1 ORF Clone (BC106762) Inquiry
CDCR375340 Rat Etv1 ORF Clone(NM_001108709.2) Inquiry
CDCR354323 Human ETV1 ORF Clone(NM_001163149.1) Inquiry
CDCR061620 Mouse Etv1 ORF clone (NM_001163154.1) Inquiry
CDCR061616 Human ETV1 ORF clone (NM_004956.4) Inquiry
CDCR061614 Human ETV1 ORF clone (NM_001163152.1) Inquiry
CDCR061612 Human ETV1 ORF clone (NM_001163151.1) Inquiry
CDCR061610 Human ETV1 ORF clone (NM_001163150.1) Inquiry
CDCR061608 Human ETV1 ORF clone (NM_001163148.1) Inquiry
CDCR061606 Human ETV1 ORF clone (NM_001163147.1) Inquiry
CDCB184337 Rabbit ETV1 ORF clone (XM_008274100.1) Inquiry
CDCB170650 Danio rerio ETV1 ORF Clone (NM_001030182) Inquiry
CDCR244621 Mouse Etv1 ORF Clone(NM_007960.4) Inquiry
CDCB166897 Chicken ETV1 ORF Clone (NM_204917) Inquiry
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