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EBP


Official Full Name
EBP cholestenol delta-isomerase
Organism
Homo sapiens
Gene ID
10682
Background
The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome). [provided by RefSeq, Jul 2008]
Synonyms
CPX; CHO2; CPXD; MEND; CDPX2

Cat.No. Product Name Price
LV11367L human EBP (NM_006579) lentivirus particles Inquiry
Cat.No. Product Name Price
SHH282805 shRNA set against Human EBP (NM_006579.2) Inquiry
SHH282809 shRNA set against Mouse EBP (NM_007898.2) Inquiry
SHH282813 shRNA set against Rat EBP (NM_057137.1) Inquiry
SHW006363 shRNA set against Danio rerio EBP (NM_001002328) Inquiry
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CDCR380778 Rat Ebp ORF Clone(NM_057137.1) Inquiry
CDFR013745 Rat Ebp cDNA Clone(NM_057137.1) Inquiry
MiUTR1M-04148 EBP miRNA 3'UTR clone Inquiry
MiUTR1R-01633 EBP miRNA 3'UTR clone Inquiry
MiUTR3H-02637 EBP miRNA 3'UTR clone Inquiry
SKO0440 EBP Validated sgRNA vector Inquiry
CDCB167838 Danio rerio EBP ORF Clone (NM_001002328) Inquiry
CDCB191856 Rabbit EBP ORF clone (XM_002719895.2) Inquiry
CDCR040359 Mouse Ebp ORF clone (NM_007898.2) Inquiry
CDCS412809 Human EBP ORF Clone (BC001549) Inquiry
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CC-433 EBP Easy KO Kit Inquiry
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