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DEPDC5


Official Full Name
DEP domain containing 5, GATOR1 subcomplex subunit
Organism
Homo sapiens
Gene ID
9681
Background
This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Synonyms
DEP.5; FFEVF; FPEVF; DEE111; FFEVF1

Cat.No. Product Name Price
SHH277173 shRNA set against Rat Depdc5 (NM_001107229.1) Inquiry
SHH277169 shRNA set against Mouse Depdc5 (NM_177786.4) Inquiry
SHH277165 shRNA set against Human Depdc5 (NM_014662.3) Inquiry
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CDFG021181 Mouse Depdc5 cDNA Clone(NM_001170567.1) Inquiry
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MiUTR3H-13168 DEPDC5 miRNA 3'UTR clone Inquiry
CDCB183338 Rabbit DEPDC5 ORF clone (XM_002719704.3) Inquiry
CDCR054994 Human DEPDC5 ORF clone (NM_001242896.1) Inquiry
CDCR054996 Human DEPDC5 ORF clone (NM_001242897.1) Inquiry
CDCR054998 Mouse Depdc5 ORF clone (NM_001170567.1) Inquiry
CDCR231638 Mouse Depdc5 ORF Clone(NM_001025426.2) Inquiry
CDCR274365 Mouse Depdc5 ORF Clone(NM_177786.4) Inquiry
CDCR297994 Human DEPDC5 ORF Clone(NM_014662.3) Inquiry
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