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CYP27B1


Official Full Name
cytochrome P450 family 27 subfamily B member 1
Organism
Homo sapiens
Gene ID
1594
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]
Synonyms
VDR; CP2B; CYP1; PDDR; VDD1; VDDR; VDDRI; CYP27B; P450c1; CYP1alpha

Cat.No. Product Name Price
SHG215899 shRNA set against Human CYP27B1(NM_000785.3) Inquiry
SHG215935 shRNA set against Rat Cyp27b1(NM_053763.1) Inquiry
SHH272981 shRNA set against Human CYP27B1 (NM_000785.3) Inquiry
SHH272985 shRNA set against Mouse CYP27B1 (NM_010009.2) Inquiry
SHH272989 shRNA set against Rat CYP27B1 (NM_053763.1) Inquiry
Cat.No. Product Name Price
CDFH004661 Human CYP27B1 cDNA Clone(NM_000785.3) Inquiry
CDFR013445 Rat Cyp27b1 cDNA Clone(NM_053763.1) Inquiry
MiUTR1H-02616 CYP27B1 miRNA 3'UTR clone Inquiry
MiUTR1R-01320 CYP27B1 miRNA 3'UTR clone Inquiry
CDCR052556 Mouse Cyp27b1 ORF clone (NM_010009.2) Inquiry
CDCR337620 Human CYP27B1 ORF Clone(NM_000785.3) Inquiry
CDCR380543 Rat Cyp27b1 ORF Clone(NM_053763.1) Inquiry
CDCS405900 Human CYP27B1 ORF Clone (BC001776) Inquiry
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