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comta


Official Full Name
catechol-O-methyltransferase a
Organism
Danio rerio
Gene ID
561372
Background
Enables catechol O-methyltransferase activity. Predicted to be involved in catecholamine catabolic process; developmental process; and dopamine metabolic process. Predicted to act upstream of or within catecholamine metabolic process and methylation. Predicted to be located in extracellular region. Is expressed in several structures, including digestive system; male organism; nervous system; pleuroperitoneal region; and unfertilized egg. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of skin and connective tissue (multiple); cognitive disorder (multiple); drug dependence (multiple); reproductive organ cancer (multiple); and withdrawal disorder (multiple). Orthologous to human COMT (catechol-O-methyltransferase). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
comt; zgc:114157

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