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CDC27


Official Full Name
cell division cycle 27
Organism
Homo sapiens
Gene ID
996
Background
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 22 and Y. [provided by RefSeq, May 2014]
Synonyms
APC3; HNUC; NUC2; H-NUC; ANAPC3; CDC27Hs; D0S1430E; D17S978E

Cat.No. Product Name Price
SHH259737 shRNA set against Rat CDC27 (NM_001024793.1) Inquiry
SHW017382 shRNA set against Danio rerio CDC27 (NM_201449) Inquiry
SHG160831 shRNA set against Mouse Cdc27(NM_145436.2) Inquiry
SHG160903 shRNA set against Human CDC27(NM_001256.3) Inquiry
SHW000417 shRNA set against Chicken CDC27 (NM_001006331) Inquiry
Cat.No. Product Name Price
CDFH003214 Human CDC27 cDNA Clone(NM_001114091.1) Inquiry
CDFL002486 Mouse Cdc27 cDNA Clone(NM_145436.2) Inquiry
CDFR003686 Rat Cdc27 cDNA Clone(NM_001024793.1) Inquiry
MiUTR1H-01939 CDC27 miRNA 3'UTR clone Inquiry
MiUTR1M-02817 CDC27 miRNA 3'UTR clone Inquiry
MiUTR1R-00872 CDC27 miRNA 3'UTR clone Inquiry
CDCB161892 Chicken CDC27 ORF Clone (NM_001006331) Inquiry
CDCB178857 Danio rerio CDC27 ORF Clone (NM_201449) Inquiry
CDCB190657 Rabbit CDC27 ORF clone (XM_002719460.2) Inquiry
CDCR044818 Mouse Cdc27 ORF clone (NM_145436.2) Inquiry
CDCR370738 Rat Cdc27 ORF Clone(NM_001024793.1) Inquiry
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