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CD226

Official Full Name
CD226 molecule
Organism
Homo sapiens
GeneID
10666
Background
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Synonyms
PTA1; DNAM1; DNAM-1; TLiSA1;

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