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CALM2


Official Full Name
calmodulin 2
Organism
Homo sapiens
Gene ID
805
Background
This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role in signaling pathways, cell cycle progression and proliferation. Several infants with severe forms of long-QT syndrome (LQTS) who displayed life-threatening ventricular arrhythmias together with delayed neurodevelopment and epilepsy were found to have mutations in either this gene or another member of the calmodulin gene family (PMID:23388215). Mutations in this gene have also been identified in patients with less severe forms of LQTS (PMID:24917665), while mutations in another calmodulin gene family member have been associated with catecholaminergic polymorphic ventricular tachycardia (CPVT)(PMID:23040497), a rare disorder thought to be the cause of a significant fraction of sudden cardiac deaths in young individuals. Pseudogenes of this gene are found on chromosomes 10, 13, and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Synonyms
caM; CALM; CAM1; CAM3; CAMC; PHKD; CAMII; LQT15; PHKD2; CALML2; CAMIII

Cat.No. Product Name Price
SHH253817 shRNA set against Human CALM2 (NM_001743.4) Inquiry
SHH253821 shRNA set against Mouse CALM2 (NM_007589.5) Inquiry
SHH253825 shRNA set against Rat CALM2 (NM_017326.1) Inquiry
SHW005506 shRNA set against Chicken CALM (NM_205005) Inquiry
SHW018648 shRNA set against Danio rerio CALM2B (NM_214736) Inquiry
Cat.No. Product Name Price
CDFR011040 Rat Calm2 cDNA Clone(NM_017326.1) Inquiry
MiUTR1R-00698 CALM2 miRNA 3'UTR clone Inquiry
MiUTR3H-00316 CALM2 miRNA 3'UTR clone Inquiry
CDCB166981 Chicken CALM ORF Clone (NM_205005) Inquiry
CDCB180123 Danio rerio CALM2B ORF Clone (NM_214736) Inquiry
CDCB180621 Rabbit CALM2 ORF clone (NM_001195640.1) Inquiry
CDCG012616 Mouse CALM2 ORF clone(NM_007589.5) Inquiry
CDCR378426 Rat Calm2 ORF Clone(NM_017326.1) Inquiry
CDCS410411 Human CALM2 ORF Clone (BC003354) Inquiry
CDCS410412 Human CALM2 ORF Clone (BC008437) Inquiry
CDCS410413 Human CALM2 ORF Clone (BC047553) Inquiry
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