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Ang2

Official Full Name
angiogenin, ribonuclease A family, member 2
Organism
Mus musculus
GeneID
11731
Background
Enables RNA nuclease activity. Involved in several processes, including angiotensin-activated signaling pathway; protein phosphorylation; and renal absorption. Acts upstream of or within cell growth involved in cardiac muscle cell development; cellular response to glucose stimulus; and positive regulation of protein phosphorylation. Predicted to be located in several cellular components, including actin cytoskeleton; basement membrane; and nucleolus. Predicted to be part of angiogenin-PRI complex. Predicted to be active in extracellular space. Is expressed in cerebral cortex; cerebral cortex subventricular zone; and cerebral cortex ventricular layer. Human ortholog(s) of this gene implicated in diabetic retinopathy; myocardial infarction; neurodegenerative disease (multiple); and prostate cancer. Orthologous to human ANG (angiogenin). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Ang2; Raa3; Angrp; Rnase5b;

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