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ACTL6A


Official Full Name
actin like 6A
Organism
Homo sapiens
Gene ID
86
Background
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms
Fam69c; B230399E16Rik

Cat.No. Product Name Price
AD00597Z Human ACTL6A adenoviral particles Inquiry
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SHH230962 shRNA set against Human ACTL6A (NM_178042.2) Inquiry
SHG036353 shRNA set against Human ACTL6A(NM_177989.2) Inquiry
SHG036371 shRNA set against Human ACTL6A(NM_004301.3) Inquiry
SHG036439 shRNA set against Rat Actl6a(NM_001039033.1) Inquiry
SHH230966 shRNA set against Mouse ACTL6A (NM_019673.2) Inquiry
SHH230970 shRNA set against Rat ACTL6A (NM_001039033.1) Inquiry
SHW015400 shRNA set against Danio rerio ACTL6A (NM_173240) Inquiry
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CDFR004675 Rat Actl6a cDNA Clone(NM_001039033.1) Inquiry
MiUTR1H-00135 ACTL6A miRNA 3'UTR clone Inquiry
MiUTR1H-00136 ACTL6A miRNA 3'UTR clone Inquiry
MiUTR1R-00094 ACTL6A miRNA 3'UTR clone Inquiry
MiUTR3H-07245 ACTL6A miRNA 3'UTR clone Inquiry
CDCB176875 Danio rerio ACTL6A ORF Clone (NM_173240) Inquiry
CDCB194460 Rabbit ACTL6A ORF clone (XM_002716442.2) Inquiry
CDCL182555 Human ACTL6A ORF clone(NM_004301.3) Inquiry
CDCR323086 Human ACTL6A ORF Clone(NM_178042.2) Inquiry
CDCR371718 Rat Actl6a ORF Clone(NM_001039033.1) Inquiry
CDCS411722 Human ACTL6A ORF Clone (BC001391) Inquiry
CDCS411723 Human ACTL6A ORF Clone (BC036371) Inquiry
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