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4921521F21RIK


Official Full Name
aldo-keto reductase family 1, member C-like
Organism
Mus musculus
Gene ID
70861
Background
Predicted to enable several functions, including geranylgeranyl reductase activity; oxidoreductase activity, acting on CH-OH group of donors; and oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Predicted to be involved in glycoside metabolic process; progesterone metabolic process; and prostaglandin metabolic process. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Is expressed in adrenal medulla; interstitium of the testis; seminiferous cord; testis; and urogenital ridge. Human ortholog(s) of this gene implicated in 46,XY sex reversal 8; B-lymphoblastic leukemia/lymphoma; T-cell acute lymphoblastic leukemia; and leukemia. Orthologous to human AKR1C1 (aldo-keto reductase family 1 member C1); AKR1C2 (aldo-keto reductase family 1 member C2); and AKR1C3 (aldo-keto reductase family 1 member C3). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
AD2; LPG; APO-E; ApoE4; LDLCQ5

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