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SF3B2


Official Full Name
splicing factor 3b subunit 2
Organism
Homo sapiens
Gene ID
10992
Background
This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]
Synonyms
CFM; HFM; Cus1; SF3b1; SAP145; SF3B145; SF3b150

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SHH405824 shRNA set against Human SF3B2 (NM_006842.2) Inquiry
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Cat.No. Product Name Price
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CDCB182911 Rabbit SF3B2 ORF clone (XM_008273507.1) Inquiry
CDCR263396 Mouse Sf3b2 ORF Clone(NM_030109.2) Inquiry
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