Pages
Products

ORC2


Official Full Name
origin recognition complex subunit 2
Organism
Homo sapiens
Gene ID
4999
Background
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010]
Synonyms
ORC2L

Cat.No. Product Name Price
SHH368412 shRNA set against Human ORC2 (NM_006190.4) Inquiry
SHH368416 shRNA set against Mouse ORC2 (NM_008765.3) Inquiry
SHH368420 shRNA set against Rat ORC2 (NM_001012003.1) Inquiry
SHR059952 shRNA set against Rat Olr186_predicted(NM_001001031.1) Inquiry
SHR080592 shRNA set against Rat Orc2l(NM_001012003.1) Inquiry
SHW000597 shRNA set against Chicken ORC2 (NM_001006517) Inquiry
Cat.No. Product Name Price
CDCR231608 Mouse Orc2 ORF Clone(NM_001025378.2) Inquiry
CDFR002432 Rat Orc2 cDNA Clone(NM_001012003.1) Inquiry
MiUTR1R-05554 ORC2 miRNA 3'UTR clone Inquiry
MiUTR3H-03933 ORC2 miRNA 3'UTR clone Inquiry
CDCB162072 Chicken ORC2 ORF Clone (NM_001006517) Inquiry
CDCB188082 Rabbit ORC2 ORF clone (XM_008258948.1) Inquiry
CDCR369350 Rat Orc2 ORF Clone(NM_001012003.1) Inquiry
CDCS412598 Human ORC2 ORF Clone (BC014834) Inquiry
Quick Inquiry