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Nlrp1a


Official Full Name
NLR family, pyrin domain containing 1A
Organism
Mus musculus
Gene ID
195046
Background
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and nucleic acid binding activity. Involved in positive regulation of interleukin-1 beta production and response to muramyl dipeptide. Acts upstream of or within defense response to bacterium and programmed necrotic cell death. Predicted to be located in nucleoplasm. Predicted to be part of NLRP1 inflammasome complex and NLRP3 inflammasome complex. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in vitiligo. Orthologous to human NLRP1 (NLR family pyrin domain containing 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Nlrp1a; NAC; Gm14; Gm15; CARD7; Nalp1; Nlrp1; DEFCAP; Nalp1a; PP1044

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