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Mll


Official Full Name
lysine (K)-specific methyltransferase 2A
Organism
Mus musculus
Gene ID
214162
Background
Enables DNA binding activity; chromatin binding activity; and histone H3K4 methyltransferase activity. Involved in circadian regulation of gene expression; definitive hemopoiesis; and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including peptidyl-lysine monomethylation; spleen development; and visual learning. Located in nucleus. Is expressed in several structures, including extraembryonic component; genitourinary system; nervous system; retina; and trunk mesenchyme. Used to study acute lymphoblastic leukemia; acute myeloid leukemia; and leukemia. Human ortholog(s) of this gene implicated in acute myeloid leukemia; cervical cancer; myelofibrosis; and non-Hodgkin lymphoma. Orthologous to human KMT2A (lysine methyltransferase 2A). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Kmt2a; HRX; Mll; All1; Mll1; ALL-1; Cxxc7; HTRX1; mKIAA4050; 6430520K01

Cat.No. Product Name Price
SHH191927 shRNA set against Human MLL(NM_001197104.1) Inquiry
SHH331799 shRNA set against Rat LOC308990 (NM_001025001.1) Inquiry
SHH342504 shRNA set against Human MLL (NM_005933.3) Inquiry
SHH342508 shRNA set against Mouse MLL (NM_139311.2) Inquiry
SHH342516 shRNA set against Mouse Mll1 (NM_001081049.1) Inquiry
SHW012011 shRNA set against Danio rerio KMT2A (NM_001110279) Inquiry
Cat.No. Product Name Price
CDFR003777 Rat LOC308990 cDNA Clone(NM_001025001.1) Inquiry
MiUTR1H-06323 MLL miRNA 3'UTR clone Inquiry
MiUTR1M-07149 MLL1 miRNA 3'UTR clone Inquiry
MiUTR1R-03152 LOC308990 miRNA 3'UTR clone Inquiry
CDCB173486 Danio rerio KMT2A ORF Clone (NM_001110279) Inquiry
CDCH390112 Human MLL ORF clone(NM_005933.3) Inquiry
CDCH390113 Mouse Mll1 ORF clone(NM_001081049.1) Inquiry
CDCR370802 Rat LOC308990 ORF Clone(NM_001025001.1) Inquiry
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