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GMNN


Official Full Name
geminin DNA replication inhibitor
Organism
Homo sapiens
Gene ID
51053
Background
This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]
Synonyms
Gem; MGORS6

Cat.No. Product Name Price
SHH090569 shRNA set against Mouse Gmnn(NM_020567.2) Inquiry
SHH304490 shRNA set against Human GMNN (NM_015895.4) Inquiry
SHH304494 shRNA set against Mouse GMNN (NM_020567.2) Inquiry
SHH304498 shRNA set against Rat GMNN (NM_001106112.1) Inquiry
SHW001633 shRNA set against Chicken GMNN (NM_001031010) Inquiry
SHW016325 shRNA set against Danio rerio GMNN (NM_200086) Inquiry
Cat.No. Product Name Price
CDCR372883 Rat Gmnn ORF Clone(NM_001106112.1) Inquiry
CDFR005872 Rat Gmnn cDNA Clone(NM_001106112.1) Inquiry
MiUTR1M-05178 GMNN miRNA 3'UTR clone Inquiry
MiUTR3H-05341 GMNN miRNA 3'UTR clone Inquiry
CDCB158638 Human GMNN ORF clone (BC005185) Inquiry
CDCB163108 Chicken GMNN ORF Clone (NM_001031010) Inquiry
CDCB177800 Danio rerio GMNN ORF Clone (NM_200086) Inquiry
CDCB187073 Rabbit GMNN ORF clone (XM_008262492.1) Inquiry
CDCR254906 Mouse Gmnn ORF Clone(NM_020567.2) Inquiry
CDCS409951 Human GMNN ORF Clone (BC005185) Inquiry
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