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GDF1


Official Full Name
growth differentiation factor 1
Organism
Homo sapiens
Gene ID
2657
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016]
Synonyms
RAI; DORV; LAG1; UOG1; CERS1; CHTD6; DTGA3; LASS1

Cat.No. Product Name Price
SHH142805 shRNA set against Human LASS1(NM_021267.3) Inquiry
SHW004070 shRNA set against Chicken CERS1 (NM_001277765) Inquiry
SHH080993 shRNA set against Human GDF1(NM_001492.4) Inquiry
SHH142823 shRNA set against Human LASS1(NM_198207.2) Inquiry
SHH262113 shRNA set against Human Cers1 (NM_021267.3) Inquiry
SHH300242 shRNA set against Human Gdf1 (NM_004864.2) Inquiry
SHH300246 shRNA set against Mouse Gdf1 (NM_008107.4) Inquiry
SHH300250 shRNA set against Rat Gdf1 (NM_001044240.2) Inquiry
SHH328611 shRNA set against Rat LASS1 (NM_001044230.2) Inquiry
Cat.No. Product Name Price
CDCR266316 Mouse Lass1 ORF Clone(NM_138647.3) Inquiry
CDFL006835 Mouse Lass1 cDNA Clone(NM_138647.3) Inquiry
CDFR004756 Rat Cers1 cDNA Clone(NM_001044230.2) Inquiry
CDFR004765 Rat Gdf1 cDNA Clone(NM_001044240.2) Inquiry
MiUTR1H-03995 GDF1 miRNA 3'UTR clone Inquiry
MiUTR1H-05580 CERS1 miRNA 3'UTR clone Inquiry
MiUTR1H-05581 CERS1 miRNA 3'UTR clone Inquiry
CDCB165545 Chicken CERS1 ORF Clone (NM_001277765) Inquiry
CDCG008988 Human GDF1 ORF clone(NM_001492.4) Inquiry
CDCG008989 Mouse GDF1 ORF clone(NM_001163282.2) Inquiry
CDCL184378 Rat GDF1 ORF clone(NM_001044240.2) Inquiry
CDCR046192 Human CERS1 ORF clone (NM_198207.2) Inquiry
CDCR244872 Mouse Gdf1 ORF Clone(NM_008107.4) Inquiry
CDCR371478 Rat Cers1 ORF Clone(NM_001044230.2) Inquiry
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