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DSC3


Official Full Name
desmocollin 3
Organism
Homo sapiens
Gene ID
1825
Background
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Synonyms
DSC; DSC1; DSC2; DSC4; CDHF3; HT-CP

Cat.No. Product Name Price
SHH016139 shRNA set against Human DSC3(NM_024423.2) Inquiry
SHH016157 shRNA set against Human DSC3(NM_001941.3) Inquiry
SHH016175 shRNA set against Mouse Dsc3(NM_007882.3) Inquiry
SHH281141 shRNA set against Human DSC3 (NM_001941.3) Inquiry
SHH281145 shRNA set against Mouse DSC3 (NM_007882.3) Inquiry
SHH281149 shRNA set against Rat DSC3 (NM_001107402.1) Inquiry
Cat.No. Product Name Price
CDFR007098 Rat Dsc3 cDNA Clone(NM_001107402.1) Inquiry
MiUTR1H-02998 DSC3 miRNA 3'UTR clone Inquiry
MiUTR1H-02999 DSC3 miRNA 3'UTR clone Inquiry
MiUTR1M-04012 DSC3 miRNA 3'UTR clone Inquiry
CDCB189527 Rabbit DSC3 ORF clone (XM_008261170.1) Inquiry
CDCR281956 Human DSC3 ORF Clone(NM_001941.3) Inquiry
CDCR374149 Rat Dsc3 ORF Clone(NM_001107402.1) Inquiry
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