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DSC2


Official Full Name
desmocollin 2
Organism
Homo sapiens
Gene ID
1824
Background
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Synonyms
DG2; DSC3; CDHF2; ARVD11; DGII/III

Cat.No. Product Name Price
SHH016103 shRNA set against Mouse Dsc2(NM_013505.3) Inquiry
SHH016121 shRNA set against Rat Dsc2(NM_001033688.1) Inquiry
SHH281129 shRNA set against Human Dsc2 (NM_004949.3) Inquiry
SHH281133 shRNA set against Mouse Dsc2 (NM_013505.3) Inquiry
SHH281137 shRNA set against Rat Dsc2 (NM_001033688.1) Inquiry
Cat.No. Product Name Price
CDFR004249 Rat Dsc2 cDNA Clone(NM_001033688.1) Inquiry
MiUTR1R-01591 DSC2 miRNA 3'UTR clone Inquiry
MiUTR4H-TG02872 DSC2 miRNA 3'UTR clone Inquiry
CDCB191001 Rabbit DSC2 ORF clone (XM_008261173.1) Inquiry
CDCH385968 Mouse DSC2 ORF clone(NM_013505.3) Inquiry
CDCL183962 Rat DSC2 ORF clone(NM_001033688.1) Inquiry
CDCR057408 Human DSC2 ORF clone (NM_004949.3) Inquiry
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